MicroRNAs: Master Regulators of Ethanol Abuse and Toxicity?
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چکیده
منابع مشابه
MicroRNAs as regulators of drug abuse and immunity
MicroRNAs (miRNAs) are 20-22 nucleotide non-coding RNAs that participate in gene regulation. They bind to 3'-untranslated regions of their mRNA targets, inhibiting the transcripts' translation and/or destabilizing them. Chronic drug abuse induces changes of miRNAs expression in the brain, which is thought to contribute to addictive behaviors. Lots of miRNAs have been identified to play critical...
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ژورنال
عنوان ژورنال: Alcoholism: Clinical and Experimental Research
سال: 2010
ISSN: 0145-6008,1530-0277
DOI: 10.1111/j.1530-0277.2009.01126.x